Michael G Irwin Selected Research

Propofol (Diprivan)

1/2020	Total Intravenous Anesthesia (TIVA) With Propofol for Acute Postoperative Pain: A Scoping Review of Randomized Controlled Trials.
8/2018	The analgesic effects of intraoperative total intravenous anesthesia (TIVA) with propofol versus sevoflurane after colorectal surgery.
1/2017	Corrigendum to "Propofol Attenuates Small Intestinal Ischemia Reperfusion Injury through Inhibiting NADPH Oxidase Mediated Mast Cell Activation".
1/2016	Effects of Intra-Operative Total Intravenous Anaesthesia with Propofol versus Inhalational Anaesthesia with Sevoflurane on Post-Operative Pain in Liver Surgery: A Retrospective Case-Control Study.
1/2015	Propofol attenuated acute kidney injury after orthotopic liver transplantation via inhibiting gap junction composed of connexin 32.
1/2015	Propofol Attenuates Small Intestinal Ischemia Reperfusion Injury through Inhibiting NADPH Oxidase Mediated Mast Cell Activation.
8/2014	Propofol ameliorates hyperglycemia-induced cardiac hypertrophy and dysfunction via heme oxygenase-1/signal transducer and activator of transcription 3 signaling pathway in rats.
1/2013	Differential microRNA profiling in a cellular hypoxia reoxygenation model upon posthypoxic propofol treatment reveals alterations in autophagy signaling network.
2/2012	Alternative use of isoflurane and propofol confers superior cardioprotection than using one of them alone in a dog model of cardiopulmonary bypass.
7/2011	Synergy of isoflurane preconditioning and propofol postconditioning reduces myocardial reperfusion injury in patients.

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Michael G Irwin Research Topics

Disease

22	Reperfusion Injury 01/2018 - 01/2009
17	Myocardial Ischemia (Ischemic Heart Diseases) 01/2020 - 01/2009
15	Hypoxia (Hypoxemia) 01/2020 - 05/2011
12	Ischemia 01/2019 - 10/2004
12	Infarction (Infarctions) 01/2019 - 10/2004
9	Pain (Aches) 12/2020 - 02/2005
9	Myocardial Infarction 01/2020 - 01/2011
8	Postoperative Pain 01/2021 - 02/2005
6	Diabetic Cardiomyopathies 01/2020 - 07/2012
6	Hyperglycemia 01/2019 - 07/2012
5	Inflammation (Inflammations) 12/2018 - 05/2013
5	Hypertrophy 07/2015 - 02/2012
3	Wounds and Injuries (Trauma) 01/2022 - 04/2013
3	Cardiomegaly (Heart Hypertrophy) 01/2016 - 08/2014
3	Body Weight (Weight, Body) 07/2015 - 07/2011
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 12/2020 - 08/2014
2	Neoplasms (Cancer) 01/2020 - 05/2013
2	Anemia 01/2020 - 01/2014
2	Heart Failure 06/2018 - 11/2015
2	Postoperative Nausea and Vomiting (PONV) 11/2015 - 05/2009
2	Hemorrhage 08/2015 - 01/2009
2	Left Ventricular Dysfunction 07/2015 - 07/2012
2	Myocardial Reperfusion Injury 07/2011 - 01/2011
2	Respiratory Insufficiency (Respiratory Failure) 05/2009 - 08/2007
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2022
1	Convalescence 01/2021
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2020
1	Breast Neoplasms (Breast Cancer) 01/2020
1	Esophageal Neoplasms (Esophageal Cancer) 01/2020
1	Cognitive Dysfunction 12/2018

Drug/Important Bio-Agent (IBA)

12	Propofol (Diprivan)FDA LinkGeneric 01/2020 - 09/2005
10	Remifentanil (Ultiva)FDA Link 01/2019 - 10/2004
9	Morphine (MS Contin)FDA LinkGeneric 08/2018 - 02/2005
8	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 01/2013
7	Isoflurane FDA LinkGeneric 01/2019 - 02/2005
6	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 01/2022 - 01/2015
6	Opioid Analgesics (Opioids)IBA 12/2020 - 10/2010
6	Proteins (Proteins, Gene)FDA Link 01/2020 - 01/2013
6	Acetylcysteine (Siran)FDA LinkGeneric 01/2019 - 01/2011
6	AntioxidantsIBA 01/2019 - 01/2011
5	Allopurinol (Remid)FDA LinkGeneric 01/2020 - 01/2011
5	AdiponectinIBA 01/2020 - 01/2011
5	Anesthetics (Anesthetic Agents)IBA 01/2020 - 11/2004
5	8-epi-prostaglandin F2alphaIBA 01/2019 - 06/2011
5	Streptozocin (Streptozotocin)FDA Link 01/2018 - 02/2012
4	Analgesics (Analgesic Drugs)IBA 01/2020 - 02/2009
4	Sevoflurane (Ultane)FDA LinkGeneric 08/2018 - 05/2015
4	Opioid Receptors (Opioid Receptor)IBA 08/2012 - 02/2005
3	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2020 - 08/2014
3	Pharmaceutical PreparationsIBA 01/2020 - 08/2007
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2019 - 04/2010
3	Protein Kinase CIBA 01/2018 - 02/2005
3	Caveolin 3IBA 01/2016 - 07/2013
3	Heme Oxygenase-1IBA 07/2015 - 01/2013
3	Reactive Oxygen Species (Oxygen Radicals)IBA 08/2014 - 06/2011
3	3-nitrotyrosineIBA 10/2013 - 03/2011
2	MicroRNAs (MicroRNA)IBA 01/2022 - 01/2016
2	alpha- cyano- (3,4- dihydroxy)- N- benzylcinnamideIBA 01/2019 - 03/2016
2	WortmanninIBA 01/2019 - 03/2016
2	Small Interfering RNA (siRNA)IBA 01/2019 - 07/2015
2	Protein Kinases (Protein Kinase)IBA 06/2018 - 08/2015
2	Doxorubicin (Adriamycin)FDA LinkGeneric 06/2018 - 11/2015
2	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2017 - 01/2015
2	salicylhydroxamic acid (SHAM)IBA 03/2016 - 04/2013
2	Phosphotransferases (Kinase)IBA 03/2016 - 01/2011
2	CreatinineIBA 03/2016 - 01/2011
2	Arginine (L-Arginine)FDA Link 05/2011 - 04/2010
1	NLR ProteinsIBA 12/2020
1	Adrenal Cortex Hormones (Corticosteroids)IBA 12/2020
1	InflammasomesIBA 12/2020
1	Dexamethasone (Maxidex)FDA LinkGeneric 12/2020
1	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 01/2020
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2019
1	5,5',6,6'- tetrachloro- 1,1',3,3'- tetraethylbenzimidazolocarbocyanineIBA 01/2019
1	CyclodextrinsIBA 01/2019
1	Neuroprotective AgentsIBA 12/2018
1	2- (2- amino- 3- methoxyphenyl)- 4H- 1- benzopyran- 4- oneIBA 06/2018
1	pyrazolanthroneIBA 06/2018
1	Blood Glucose (Blood Sugar)IBA 01/2018
1	Hypoglycemic Agents (Hypoglycemics)IBA 01/2018
1	dorsomorphinIBA 01/2018
1	pterostilbeneIBA 01/2018

Therapy/Procedure

4	Anesthesia 01/2020 - 02/2005
3	Intravenous Anesthesia 01/2020 - 01/2016
2	Ischemic Postconditioning 01/2020 - 01/2016
2	Operative Surgical Procedures 01/2020 - 11/2015
2	Analgesia 10/2015 - 08/2007
2	Therapeutics 01/2015 - 02/2012
1	Enhanced Recovery After Surgery 01/2021
1	Knee Replacement Arthroplasty (Total Knee Replacement) 12/2020
1	Epidural Analgesia 01/2020
1	Abdominoplasty 01/2020
1	Gynecologic Surgical Procedures (Gynecologic Surgery) 01/2020
1	Bariatric Surgery 01/2020
1	Ligation 01/2020
1	Esophagectomy 01/2020
1	Gastrectomy 01/2020
1	Fluid Therapy (Oral Rehydration Therapy) 01/2020
1	Cholecystectomy 01/2020
1	Preoperative Exercise 01/2020